Non-Animal Methods in Science and Regulation

Non-Animal Methods in Science and Regulation / EURL ECVAM Status Report 2025 - JRC January 2026

ID 25911 | 02.04.2026

The 2025 EURL ECVAM Status Report presents a comprehensive overview of recent advancements of the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) in the development, validation, and regulatory integration of non-animal methods, as well as progress made elsewhere. Anchored in the EU’s

Three Rs framework of Replacement, Reduction, and Refinement, this report highlights innovative scientific breakthroughs including organ-on-chip technologies, artificial intelligence, and multiomics approaches that collectively enhance the predictivity, efficiency, and ethical standards of safety assessment.

EURL ECVAM’s active participation in Horizon Europe initiatives, international standardisation efforts, and strategic partnerships reinforces its pivotal role in fostering a robust, innovationdriven ecosystem.

With the European Commission preparing to publish in 2026 a roadmap for phasing out animal testing, this status report serves as a critical resource documenting scientific, regulatory, societal, and economic progress.

It underlines EURL ECVAM’s commitment to evolving animal-free approaches that not only uphold EU ethical values but also promote sustainable growth, competitiveness, and public health outcomes in Europe and beyond.
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	Descrizione	Lingua	Dimensioni	Downloads
	Non-Animal Methods in Science and Regulation - EURL ECVAM Status Report 2025 JRC January 2026	EN	2799 kB	12